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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN1 All Species: 16.06
Human Site: S562 Identified Species: 27.18
UniProt: Q16512 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16512 NP_002732.3 942 103932 S562 L G T D S D S S P Q K S S R D
Chimpanzee Pan troglodytes XP_512443 1169 127241 S789 L G T D S D S S P Q K S S R D
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 T614 S N F L P K K T P L G E E M T
Dog Lupus familis XP_542019 1076 118222 L695 L G T A L D S L P Q K S P L G
Cat Felis silvestris
Mouse Mus musculus P70268 946 104392 S565 L G A D S D S S S Q K S P P G
Rat Rattus norvegicus Q63433 946 104449 S565 L G A D S D S S S Q K S P A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 L602 A S P F P L T L E E E D P P P
Chicken Gallus gallus XP_422357 1013 114806 D586 E L A L Q A S D S P V A K L D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689331 948 107057 K571 L D F D S P M K V D I R R E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 G288 V T G S G G V G A T G E T R P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 S361 E D D S G T T S S R S A S K V
Sea Urchin Strong. purpuratus XP_787090 799 90414 S422 F D F L N N S S S S S P K V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 T747 D F R E A D L T I D S T H T N
Red Bread Mold Neurospora crassa P87253 1142 127954 G720 A Q Q Q Q G Y G S P Q Q R K Y
Conservation
Percent
Protein Identity: 100 79.3 38.7 83 N.A. 91.6 91.9 N.A. 42.2 57.6 N.A. 66.7 N.A. 29 N.A. 27.8 48.5
Protein Similarity: 100 79.9 52.6 84.3 N.A. 94.7 94.6 N.A. 56.1 72.1 N.A. 79.5 N.A. 42.8 N.A. 43.4 61.7
P-Site Identity: 100 100 6.6 60 N.A. 66.6 66.6 N.A. 0 13.3 N.A. 20 N.A. 6.6 N.A. 13.3 13.3
P-Site Similarity: 100 100 13.3 60 N.A. 66.6 66.6 N.A. 20 20 N.A. 20 N.A. 20 N.A. 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 28.3
Protein Similarity: N.A. N.A. N.A. N.A. 44.4 45.1
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 22 8 8 8 0 0 8 0 0 15 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 22 8 36 0 43 0 8 0 15 0 8 0 0 22 % D
% Glu: 15 0 0 8 0 0 0 0 8 8 8 15 8 8 0 % E
% Phe: 8 8 22 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 36 8 0 15 15 0 15 0 0 15 0 0 0 22 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 8 0 0 36 0 15 15 0 % K
% Leu: 43 8 0 22 8 8 8 15 0 8 0 0 0 15 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 0 8 8 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 8 0 15 8 0 0 29 15 0 8 29 15 15 % P
% Gln: 0 8 8 8 15 0 0 0 0 36 8 8 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 8 0 8 15 22 0 % R
% Ser: 8 8 0 15 36 0 50 43 43 8 22 36 22 0 8 % S
% Thr: 0 8 22 0 0 8 15 15 0 8 0 8 8 8 8 % T
% Val: 8 0 0 0 0 0 8 0 8 0 8 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _